Cargando…

HDAC Inhibition Induces Cell Cycle Arrest and Mesenchymal-Epithelial Transition in a Novel Pleural-Effusion Derived Uterine Carcinosarcoma Cell Line

Objective: Uterine carcinosarcoma (UCS) is a rare but highly aggressive malignancy with biphasic growth pattern. This morphology can be attributed to epithelial-mesenchymal transition (EMT) that often associates with tumor invasion and metastasis. Accordingly, we analyzed a novel patient-derived pre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stockhammer, Paul, Okumus, Özlem, Hegedus, Luca, Rittler, Dominika, Ploenes, Till, Herold, Thomas, Kalbourtzis, Stavros, Bankfalvi, Agnes, Sucker, Antje, Kimmig, Rainer, Aigner, Clemens, Hegedus, Balazs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Society Journal Archive
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262245/ https://www.ncbi.nlm.nih.gov/pubmed/34257602 http://dx.doi.org/10.3389/pore.2021.636088

Ejemplares similares

HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line
por: Hegedűs, Luca, et al.
Publicado: (2020)

Cell-free DNA From Pleural Effusion Samples: Is It Right for Molecular Testing in Lung Adenocarcinoma?
por: Mokánszki, Attila, et al.
Publicado: (2021)

Potential Prognostic Value of Preoperative Leukocyte Count, Lactate Dehydrogenase and C-Reactive Protein in Thymic Epithelial Tumors
por: Valdivia, Daniel, et al.
Publicado: (2021)

Allosteric and ATP-Competitive MEK-Inhibition in a Novel Spitzoid Melanoma Model with a RAF- and Phosphorylation-Independent Mutation
por: Hegedüs, Luca, et al.
Publicado: (2021)

Tumour cell PD-L1 expression is prognostic in patients with malignant pleural effusion: the impact of C-reactive protein and immune-checkpoint inhibition
por: Ghanim, Bahil, et al.
Publicado: (2020)

EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas
por: Nelhűbel, Györgyi A., et al.
Publicado: (2021)

Horizontal Combination of MEK and PI3K/mTOR Inhibition in BRAF Mutant Tumor Cells with or without Concomitant PI3K Pathway Mutations
por: Rittler, Dominika, et al.
Publicado: (2020)

Implementation of an experimental isolated lung perfusion model on surgically resected human lobes
por: Slama, Alexis, et al.
Publicado: (2019)

New strategies to manage complicated pleural effusions
por: Safiyeh, Majed, et al.
Publicado: (2012)

Diagnostic Utility of BAP1, EZH2 and Survivin in Differentiating Pleural Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia: Immunohistochemical Study
por: Hakim, Sarah Adel, et al.
Publicado: (2021)

The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb
por: Rittler, Dominika, et al.
Publicado: (2019)

Effusion cytology of metastatic carcinosarcoma
por: Kundu, Reetu, et al.
Publicado: (2023)

Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma
por: Borchert, Sabrina, et al.
Publicado: (2020)

The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition
por: Hegedüs, Luca, et al.
Publicado: (2022)

Diagnostic Value of Six Tumor Markers for Malignant Pleural Effusion in 1,230 Patients: A Single-Center Retrospective Study
por: Fan, Xin, et al.
Publicado: (2022)

Screening of Pleural Mesothelioma Cell Lines for Kinase Activity May Identify New Mechanisms of Therapy Resistance in Patients Receiving Platin-Based Chemotherapy
por: Borchert, Sabrina, et al.
Publicado: (2019)

Dataset of a study investigating autologous blood patch pleurodesis in postoperative prolonged air leaks after lung resection
por: Ploenes, Till, et al.
Publicado: (2020)

Insights into immunometabolism: A dataset correlating the (18)FDG PET/CT maximum standard uptake value of the primary tumor with the CCL18 serum level in non-small cell lung cancer
por: Dönmez, Tugba, et al.
Publicado: (2021)

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
por: Molnár, Eszter, et al.
Publicado: (2018)

Editorial: The Need for Harmonised International Guidelines ahead of COVID-19 Human Infection Studies
por: Kirchhelle, Claas, et al.
Publicado: (2021)

The Burden of Drug Abuse in Nigeria: A Scoping Review of Epidemiological Studies and Drug Laws
por: Jatau, Abubakar Ibrahim, et al.
Publicado: (2021)

The Impact of Sarcopenia in Patients with Peritoneal Surface Disease
por: Juris, Aubrey, et al.
Publicado: (2021)

Risk and Protective Factors Associated With Support of Violent Radicalization: Variations by Geographic Location
por: Ellis, B. Heidi, et al.
Publicado: (2021)

Influence of a University Tobacco-Free Policy on the Attitudes, Perceptions of Compliance, and Policy Benefit Among the University Students: A Pre-Post Investigation
por: Chaaya, Monique, et al.
Publicado: (2021)

Commentary: Some Social, Psychological, and Political Factors That Undermine Compliance With COVID-19 Public Health Measures
por: Magnus, Kathleen D.
Publicado: (2021)

Are Social Relationships an Underestimated Resource for Mental Health in Persons Experiencing Physical Disability? Observational Evidence From 22 Countries
por: Fekete, Christine, et al.
Publicado: (2021)

Historical Trends in Incidence of Breast Cancer in Shanghai, Hong Kong and Los Angeles, 1973–2012: A Joinpoint and Age-Period-Cohort Analysis
por: Luan, Hang-Hang, et al.
Publicado: (2021)

The Association Between Ideal Cardiovascular Health and Health-Related Quality of Life in Adults: A Population-Based Cross-Sectional Study
por: Wu, Xueyan, et al.
Publicado: (2021)

Attitudes Toward COVID-19 Vaccination Among Young Adults in Zurich, Switzerland, September 2020
por: Leos-Toro, Cesar, et al.
Publicado: (2021)

What Regional Living Conditions Affect Individual Smoking of Adults in Russia
por: Maksimov, Sergey A., et al.
Publicado: (2021)

Socio-Environmental Vulnerability Index: An Application to Rio de Janeiro-Brazil
por: Malta, Fernanda Siqueira, et al.
Publicado: (2021)

Can Big Data Be Used to Monitor the Mental Health Consequences of COVID-19?
por: Aebi, Nicola Julia, et al.
Publicado: (2021)

Public Preferences for Exit Strategies From COVID-19 Lockdown in Germany—A Discrete Choice Experiment
por: Krauth, Christian, et al.
Publicado: (2021)

Burden of Disease Methods: A Guide to Calculate COVID-19 Disability-Adjusted Life Years
por: Wyper, Grant M. A., et al.
Publicado: (2021)

Impact of the COVID-19 Pandemic on the Intensity of Health Services Use in General Practice: A Retrospective Cohort Study
por: Rachamin, Yael, et al.
Publicado: (2021)

Trends in Tobacco Smoking in Pregnant Women: Data From French National Perinatal Surveys
por: Demiguel, Virginie, et al.
Publicado: (2021)

Employment Status and Health Literacy in Denmark: A Population-Based Study
por: Svendsen, Ida W., et al.
Publicado: (2021)

The Association of Family-Related Adversity With Fighting in Adolescents: Does Hopelessness Mediate This Association?
por: Macková, Jaroslava, et al.
Publicado: (2021)

Transport to School and Mental Well-Being of Schoolchildren in Ireland
por: Költő, András, et al.
Publicado: (2021)

Early-Life Exposure to the Chinese Great Famine and Later Cardiovascular Diseases
por: Wang, Zhenghe, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8j272nodh5n2u6vv9ih9g2eh28