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Double-jeopardy: scRNA-seq doublet/multiplet detection using multi-omic profiling
The computational detection and exclusion of cellular doublets and/or multiplets is a cornerstone for the identification the true biological signals from single-cell RNA sequencing (scRNA-seq) data. Current methods do not sensitively identify both heterotypic and homotypic doublets and/or multiplets...
Autores principales: | Sun, Bo, Bugarin-Estrada, Emmanuel, Overend, Lauren Elizabeth, Walker, Catherine Elizabeth, Tucci, Felicia Anna, Bashford-Rogers, Rachael Jennifer Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262260/ https://www.ncbi.nlm.nih.gov/pubmed/34278374 http://dx.doi.org/10.1016/j.crmeth.2021.100008 |
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