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ATI-2307 Exhibits Equivalent Antifungal Activity in Cryptococcus neoformans Clinical Isolates With High and Low Fluconazole IC(50)
Half maximal inhibitory concentrations (IC(50)) to the experimental drug ATI-2307 and complete inhibition (IC(90)) of the common clinically used antifungal drug amphotericin B were determined by microbroth dilution assay for a collection of 69 clinical isolates of Cryptococcus neoformans from Uganda...
Autores principales: | Gerlach, Elliot S., Altamirano, Sophie, Yoder, J. Marina, Luggya, Tony S., Akampurira, Andrew, Meya, David B., Boulware, David R., Rhein, Joshua, Nielsen, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262267/ https://www.ncbi.nlm.nih.gov/pubmed/34249782 http://dx.doi.org/10.3389/fcimb.2021.695240 |
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