Epithelial miR-206 targets CD39/extracellular ATP to upregulate airway IL-25 and TSLP in type 2–high asthma

The epithelial cell–derived cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) initiate type 2 inflammation in allergic diseases, including asthma. However, the signaling pathway regulating these cytokines expression remains elusive. Since microRNAs are pivotal regulators of gene expres...

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Detalles Bibliográficos
Autores principales: Zhang, Kan, Feng, Yuchen, Liang, Yuxia, Wu, Wenliang, Chang, Chenli, Chen, Dian, Chen, Shengchong, Gao, Jiali, Chen, Gongqi, Yi, Lingling, Cheng, Dan, Zhen, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262281/
https://www.ncbi.nlm.nih.gov/pubmed/33945508
http://dx.doi.org/10.1172/jci.insight.148103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262281/
https://www.ncbi.nlm.nih.gov/pubmed/33945508
http://dx.doi.org/10.1172/jci.insight.148103

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