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Epithelial miR-206 targets CD39/extracellular ATP to upregulate airway IL-25 and TSLP in type 2–high asthma
The epithelial cell–derived cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) initiate type 2 inflammation in allergic diseases, including asthma. However, the signaling pathway regulating these cytokines expression remains elusive. Since microRNAs are pivotal regulators of gene expres...
Autores principales: | Zhang, Kan, Feng, Yuchen, Liang, Yuxia, Wu, Wenliang, Chang, Chenli, Chen, Dian, Chen, Shengchong, Gao, Jiali, Chen, Gongqi, Yi, Lingling, Cheng, Dan, Zhen, Guohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262281/ https://www.ncbi.nlm.nih.gov/pubmed/33945508 http://dx.doi.org/10.1172/jci.insight.148103 |
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