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HIV-1 integration sites in CD4(+) T cells during primary, chronic, and late presentation of HIV-1 infection
HIV-1 is capable of integrating its genome into that of its host cell. We examined the influence of the activation state of CD4(+) T cells, the effect of antiretroviral therapy (ART), and the clinical stage of HIV-1 infection on HIV-1 integration site features and selection. HIV-1 integration sites...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262285/ https://www.ncbi.nlm.nih.gov/pubmed/33784259 http://dx.doi.org/10.1172/jci.insight.143940 |