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HIV-1 integration sites in CD4(+) T cells during primary, chronic, and late presentation of HIV-1 infection

HIV-1 is capable of integrating its genome into that of its host cell. We examined the influence of the activation state of CD4(+) T cells, the effect of antiretroviral therapy (ART), and the clinical stage of HIV-1 infection on HIV-1 integration site features and selection. HIV-1 integration sites...

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Detalles Bibliográficos
Autores principales: Kok, Yik Lim, Vongrad, Valentina, Chaudron, Sandra E., Shilaih, Mohaned, Leemann, Christine, Neumann, Kathrin, Kusejko, Katharina, Di Giallonardo, Francesca, Kuster, Herbert, Braun, Dominique L., Kouyos, Roger D., Günthard, Huldrych F., Metzner, Karin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262285/
https://www.ncbi.nlm.nih.gov/pubmed/33784259
http://dx.doi.org/10.1172/jci.insight.143940