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Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection

Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi (T. cruzi), an intracellular pathogen that causes significant morbidity and death among millions in the Americas from Canada to Argentina. Current therapy involves oral administration of the nitroimidazole benznidazo...

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Detalles Bibliográficos
Autores principales:	Li, Xiaomo, Yi, Sijia, Scariot, Débora B., Martinez, Santiago J., Falk, Ben A., Olson, Cheryl L., Romano, Patricia S., Scott, Evan A., Engman, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262286/ https://www.ncbi.nlm.nih.gov/pubmed/33986194 http://dx.doi.org/10.1172/jci.insight.145523

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