Optogenetic modulation of cardiac action potential properties may prevent arrhythmogenesis in short and long QT syndromes

Abnormal action potential (AP) properties, as occurs in long or short QT syndromes (LQTS and SQTS, respectively), can cause life-threatening arrhythmias. Optogenetics strategies, utilizing light-sensitive proteins, have emerged as experimental platforms for cardiac pacing, resynchronization, and def...

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Detalles Bibliográficos
Autores principales: Gruber, Amit, Edri, Oded, Huber, Irit, Arbel, Gil, Gepstein, Amira, Shiti, Assad, Shaheen, Naim, Chorna, Snizhana, Landesberg, Michal, Gepstein, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262308/
https://www.ncbi.nlm.nih.gov/pubmed/34100384
http://dx.doi.org/10.1172/jci.insight.147470

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