NK cells associate with ALS in a sex- and age-dependent manner

NK cells are innate immune cells implicated in ALS; whether NK cells impact ALS in a sex- and age-specific manner was investigated. Herein, NK cells were depleted in male and female SOD1(G93A) ALS mice, survival and neuroinflammation were assessed, and data were stratified by sex. NK cell depletion...

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Detalles Bibliográficos
Autores principales: Murdock, Benjamin J., Famie, Joshua P., Piecuch, Caroline E., Pawlowski, Kristen D., Mendelson, Faye E., Pieroni, Cole H., Iniguez, Sebastian D., Zhao, Lili, Goutman, Stephen A., Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262328/
https://www.ncbi.nlm.nih.gov/pubmed/33974561
http://dx.doi.org/10.1172/jci.insight.147129

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