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Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling

Excessive proliferation of vascular smooth muscle cells (SMCs) remains a significant cause of in-stent restenosis. Integrins, which are heterodimeric transmembrane receptors, play a crucial role in SMC biology by binding to the extracellular matrix protein with the actin cytoskeleton within the SMC....

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Detalles Bibliográficos
Autores principales: Jain, Manish, Dev, Rishabh, Doddapattar, Prakash, Kon, Shigeyuki, Dhanesha, Nirav, Chauhan, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262341/
https://www.ncbi.nlm.nih.gov/pubmed/34027892
http://dx.doi.org/10.1172/jci.insight.147134