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Adipocyte P2Y(14) receptors play a key role in regulating whole-body glucose and lipid homeostasis
Obesity is the major driver of the worldwide epidemic in type 2 diabetes (T2D). In the obese state, chronically elevated plasma free fatty acid levels contribute to peripheral insulin resistance, which can ultimately lead to the development of T2D. For this reason, drugs that are able to regulate li...
Autores principales: | Jain, Shanu, Pydi, Sai P., Jung, Young-Hwan, Scortichini, Mirko, Kesner, Efrat L., Karcz, Tadeusz P., Cook, Donald N., Gavrilova, Oksana, Wess, Jürgen, Jacobson, Kenneth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262345/ https://www.ncbi.nlm.nih.gov/pubmed/34027896 http://dx.doi.org/10.1172/jci.insight.146577 |
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