miR–9-5p regulates immunometabolic and epigenetic pathways in β-glucan–trained immunity via IDH3α

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Trained immunity, induced by β-glucan in monocytes, is mediated by activating metabolic pathways that result in epigenetic rewiring of cellular functional programs; however, molecular mechanisms underlying these changes remain unclear. Here, we report a key immunometabolic and epigenetic pathway med...

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Detalles Bibliográficos
Autores principales: Su, Haibo, Liang, Zhongping, Weng, ShuFeng, Sun, Chaonan, Huang, Jiaxin, Zhang, TianRan, Wang, Xialian, Wu, Shanshan, Zhang, Zhi, Zhang, Yiqi, Gong, Qing, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262351/
https://www.ncbi.nlm.nih.gov/pubmed/33986196
http://dx.doi.org/10.1172/jci.insight.144260

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