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Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have focused on systemic immunization, here we compared the protective efficacy of 2 adjuvanted subunit vaccines with spike protein S1: an intramuscularly primed/boosted vaccine and an intramuscularly primed/intranas...

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Detalles Bibliográficos
Autores principales: Sui, Yongjun, Li, Jianping, Zhang, Roushu, Prabhu, Sunaina Kiran, Andersen, Hanne, Venzon, David, Cook, Anthony, Brown, Renita, Teow, Elyse, Velasco, Jason, Greenhouse, Jack, Putman-Taylor, Tammy, Campbell, Tracey-Ann, Pessaint, Laurent, Moore, Ian N., Lagenaur, Laurel, Talton, Jim, Breed, Matthew W., Kramer, Josh, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Lewis, Mark G., Wang, Lai-Xi, Berzofsky, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262352/
https://www.ncbi.nlm.nih.gov/pubmed/33908897
http://dx.doi.org/10.1172/jci.insight.148494