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A CD44/Brg1 nuclear complex confers mesenchymal progenitor cells with enhanced fibrogenicity in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease. We previously identified fibrogenic mesenchymal progenitor cells (MPCs) in the lungs of patients with IPF who serve as drivers of progressive fibrosis. Recent single-cell RNA sequencing work revealed that IPF MPCs with the h...

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Detalles Bibliográficos
Autores principales:	Yang, Libang, Xia, Hong, Smith, Karen, Gilbertsen, Adam, Beisang, Daniel, Kuo, Jonathan, Bitterman, Peter B., Henke, Craig A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262361/ https://www.ncbi.nlm.nih.gov/pubmed/33822772 http://dx.doi.org/10.1172/jci.insight.144652

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