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Rap1 in the VMH regulates glucose homeostasis
The hypothalamus is a critical regulator of glucose metabolism and is capable of correcting diabetes conditions independently of an effect on energy balance. The small GTPase Rap1 in the forebrain is implicated in high-fat diet–induced (HFD-induced) obesity and glucose imbalance. Here, we report tha...
Autores principales: | Kaneko, Kentaro, Lin, Hsiao-Yun, Fu, Yukiko, Saha, Pradip K., De la Puente-Gomez, Ana B., Xu, Yong, Ohinata, Kousaku, Chen, Peter, Morozov, Alexei, Fukuda, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262364/ https://www.ncbi.nlm.nih.gov/pubmed/33974562 http://dx.doi.org/10.1172/jci.insight.142545 |
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