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T-bet(+)CD27(+)CD21(–) B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants
Alloimmune responses driven by donor-specific antibodies (DSAs) can lead to antibody-mediated rejection (ABMR) in organ transplantation. Yet, the cellular states underlying alloreactive B cell responses and the molecular components controlling them remain unclear. Using high-dimensional profiling of...
Autores principales: | Louis, Kevin, Bailly, Elodie, Macedo, Camila, Lau, Louis, Ramaswami, Bala, Chang, Alexander, Chandran, Uma, Landsittel, Douglas, Gu, Xinyan, Chalasani, Geetha, Zeevi, Adriana, Randhawa, Parmjeet, Singh, Harinder, Lefaucheur, Carmen, Metes, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262465/ https://www.ncbi.nlm.nih.gov/pubmed/34032636 http://dx.doi.org/10.1172/jci.insight.148881 |
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