A role for IL-33–activated ILC2s in eosinophilic vasculitis

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare but serious disease with poorly understood mechanisms. Here, we report that patients with EGPA have elevated levels of TSLP, IL-25, and soluble ST2, which are well-characterized cytokine “alarmins” that activate or modulate type 2 innate...

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Detalles Bibliográficos
Autores principales: Kotas, Maya E., Dion, Jérémie, Van Dyken, Steven, Ricardo-Gonzalez, Roberto R., Danel, Claire J., Taillé, Camille, Mouthon, Luc, Locksley, Richard M., Terrier, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262498/
https://www.ncbi.nlm.nih.gov/pubmed/33974563
http://dx.doi.org/10.1172/jci.insight.143366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262498/
https://www.ncbi.nlm.nih.gov/pubmed/33974563
http://dx.doi.org/10.1172/jci.insight.143366

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