Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting

PDCD10, also known as CCM3, is a gene found to be associated with the human disease cerebral cavernous malformations (CCMs). PDCD10 forms a complex with GCKIII kinases including STK24, STK25, and MST4. Studies in C. elegans and Drosophila have shown a pivotal role of the PDCD10-GCKIII complex in mai...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Wu, Shi-Ting, Yang, Xi, Qian, Yude, Choi, Jaesung P., Gao, Rui, Song, Siliang, Wang, Yixuan, Zhuang, Tao, Wong, Justin J.L., Zhang, Yuzhen, Han, Zhiming, Lu, Hua A., Alexander, Stephen I., Liu, Renjing, Xia, Yin, Zheng, Xiangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262504/
https://www.ncbi.nlm.nih.gov/pubmed/34156031
http://dx.doi.org/10.1172/jci.insight.142838

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