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Translational Control of Immune Evasion in Cancer

Mechanisms that control translation play important roles in tumor progression and metastasis. Emerging evidence has revealed that dysregulated translation also impacts immune evasion in response to cellular or oncogenic stress. Here, we summarize current knowledge regarding the translational control...

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Detalles Bibliográficos
Autores principales: Suresh, Shruthy, O’Donnell, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262573/
https://www.ncbi.nlm.nih.gov/pubmed/33972197
http://dx.doi.org/10.1016/j.trecan.2021.04.002
Descripción
Sumario:Mechanisms that control translation play important roles in tumor progression and metastasis. Emerging evidence has revealed that dysregulated translation also impacts immune evasion in response to cellular or oncogenic stress. Here, we summarize current knowledge regarding the translational control of immune checkpoints and implications for cancer immunotherapies.