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ProteinTools: a toolkit to analyze protein structures

The experimental characterization and computational prediction of protein structures has become increasingly rapid and precise. However, the analysis of protein structures often requires researchers to use several software packages or web servers, which complicates matters. To provide long-establish...

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Detalles Bibliográficos
Autores principales: Ferruz, Noelia, Schmidt, Steffen, Höcker, Birte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262690/
https://www.ncbi.nlm.nih.gov/pubmed/34019657
http://dx.doi.org/10.1093/nar/gkab375
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author Ferruz, Noelia
Schmidt, Steffen
Höcker, Birte
author_facet Ferruz, Noelia
Schmidt, Steffen
Höcker, Birte
author_sort Ferruz, Noelia
collection PubMed
description The experimental characterization and computational prediction of protein structures has become increasingly rapid and precise. However, the analysis of protein structures often requires researchers to use several software packages or web servers, which complicates matters. To provide long-established structural analyses in a modern, easy-to-use interface, we implemented ProteinTools, a web server toolkit for protein structure analysis. ProteinTools gathers four applications so far, namely the identification of hydrophobic clusters, hydrogen bond networks, salt bridges, and contact maps. In all cases, the input data is a PDB identifier or an uploaded structure, whereas the output is an interactive dynamic web interface. Thanks to the modular nature of ProteinTools, the addition of new applications will become an easy task. Given the current need to have these tools in a single, fast, and interpretable interface, we believe that ProteinTools will become an essential toolkit for the wider protein research community. The web server is available at https://proteintools.uni-bayreuth.de.
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spelling pubmed-82626902021-07-08 ProteinTools: a toolkit to analyze protein structures Ferruz, Noelia Schmidt, Steffen Höcker, Birte Nucleic Acids Res Web Server Issue The experimental characterization and computational prediction of protein structures has become increasingly rapid and precise. However, the analysis of protein structures often requires researchers to use several software packages or web servers, which complicates matters. To provide long-established structural analyses in a modern, easy-to-use interface, we implemented ProteinTools, a web server toolkit for protein structure analysis. ProteinTools gathers four applications so far, namely the identification of hydrophobic clusters, hydrogen bond networks, salt bridges, and contact maps. In all cases, the input data is a PDB identifier or an uploaded structure, whereas the output is an interactive dynamic web interface. Thanks to the modular nature of ProteinTools, the addition of new applications will become an easy task. Given the current need to have these tools in a single, fast, and interpretable interface, we believe that ProteinTools will become an essential toolkit for the wider protein research community. The web server is available at https://proteintools.uni-bayreuth.de. Oxford University Press 2021-05-21 /pmc/articles/PMC8262690/ /pubmed/34019657 http://dx.doi.org/10.1093/nar/gkab375 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Web Server Issue
Ferruz, Noelia
Schmidt, Steffen
Höcker, Birte
ProteinTools: a toolkit to analyze protein structures
title ProteinTools: a toolkit to analyze protein structures
title_full ProteinTools: a toolkit to analyze protein structures
title_fullStr ProteinTools: a toolkit to analyze protein structures
title_full_unstemmed ProteinTools: a toolkit to analyze protein structures
title_short ProteinTools: a toolkit to analyze protein structures
title_sort proteintools: a toolkit to analyze protein structures
topic Web Server Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262690/
https://www.ncbi.nlm.nih.gov/pubmed/34019657
http://dx.doi.org/10.1093/nar/gkab375
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