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DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web
Understanding the functions of proteins is crucial to understand biological processes on a molecular level. Many more protein sequences are available than can be investigated experimentally. DeepGOPlus is a protein function prediction method based on deep learning and sequence similarity. DeepGOWeb...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262746/ https://www.ncbi.nlm.nih.gov/pubmed/34019664 http://dx.doi.org/10.1093/nar/gkab373 |
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author | Kulmanov, Maxat Zhapa-Camacho, Fernando Hoehndorf, Robert |
author_facet | Kulmanov, Maxat Zhapa-Camacho, Fernando Hoehndorf, Robert |
author_sort | Kulmanov, Maxat |
collection | PubMed |
description | Understanding the functions of proteins is crucial to understand biological processes on a molecular level. Many more protein sequences are available than can be investigated experimentally. DeepGOPlus is a protein function prediction method based on deep learning and sequence similarity. DeepGOWeb makes the prediction model available through a website, an API, and through the SPARQL query language for interoperability with databases that rely on Semantic Web technologies. DeepGOWeb provides accurate and fast predictions and ensures that predicted functions are consistent with the Gene Ontology; it can provide predictions for any protein and any function in Gene Ontology. DeepGOWeb is freely available at https://deepgo.cbrc.kaust.edu.sa/. |
format | Online Article Text |
id | pubmed-8262746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-82627462021-07-08 DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web Kulmanov, Maxat Zhapa-Camacho, Fernando Hoehndorf, Robert Nucleic Acids Res Web Server Issue Understanding the functions of proteins is crucial to understand biological processes on a molecular level. Many more protein sequences are available than can be investigated experimentally. DeepGOPlus is a protein function prediction method based on deep learning and sequence similarity. DeepGOWeb makes the prediction model available through a website, an API, and through the SPARQL query language for interoperability with databases that rely on Semantic Web technologies. DeepGOWeb provides accurate and fast predictions and ensures that predicted functions are consistent with the Gene Ontology; it can provide predictions for any protein and any function in Gene Ontology. DeepGOWeb is freely available at https://deepgo.cbrc.kaust.edu.sa/. Oxford University Press 2021-05-21 /pmc/articles/PMC8262746/ /pubmed/34019664 http://dx.doi.org/10.1093/nar/gkab373 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Web Server Issue Kulmanov, Maxat Zhapa-Camacho, Fernando Hoehndorf, Robert DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web |
title | DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web |
title_full | DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web |
title_fullStr | DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web |
title_full_unstemmed | DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web |
title_short | DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web |
title_sort | deepgoweb: fast and accurate protein function prediction on the (semantic) web |
topic | Web Server Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262746/ https://www.ncbi.nlm.nih.gov/pubmed/34019664 http://dx.doi.org/10.1093/nar/gkab373 |
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