Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Bladder cancer, one of the most prevalent malignancies worldwide, remains hard to classify due to a staggering molecular complexity. Despite a plethora of diagnostic tools and therapies, it is hard to outline the key steps leading up to the transition from high-risk non–muscle-invasive bladder cance...

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Detalles Bibliográficos
Autores principales: Kerzeli, Iliana K., Lord, Martin, Doroszko, Milena, Elgendy, Ramy, Chourlia, Aikaterini, Stepanek, Ivan, Larsson, Elinor, van Hooren, Luuk, Nelander, Sven, Malmstrom, Per-Uno, Dragomir, Anca, Segersten, Ulrika, Mangsbo, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262791/
https://www.ncbi.nlm.nih.gov/pubmed/34232958
http://dx.doi.org/10.1371/journal.pone.0253178

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