The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profile

Intratumoral heterogeneity is a driver of breast cancer progression, but the nature of the clonal interactive network involved in this process remains unclear. Here, we optimized the use of optical barcoding to visualize and characterize 31 cancer subclones in vivo. By mapping the clonal composition...

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Detalles Bibliográficos
Autores principales: Berthelet, Jean, Wimmer, Verena C., Whitfield, Holly J., Serrano, Antonin, Boudier, Thomas, Mangiola, Stefano, Merdas, Michal, El-Saafin, Farrah, Baloyan, David, Wilcox, Jordan, Wilcox, Steven, Parslow, Adam C., Papenfuss, Anthony T., Yeo, Belinda, Ernst, Matthias, Pal, Bhupinder, Anderson, Robin L., Davis, Melissa J., Rogers, Kelly L., Hollande, Frédéric, Merino, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262813/
https://www.ncbi.nlm.nih.gov/pubmed/34233875
http://dx.doi.org/10.1126/sciadv.abf4408

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