Restructured Mitochondrial-Nuclear Interaction in Plasmodium falciparum Dormancy and Persister Survival after Artemisinin Exposure

Artemisinin and its semisynthetic derivatives (ART) are fast acting, potent antimalarials; however, their use in malaria treatment is frequently confounded by recrudescences from bloodstream Plasmodium parasites that enter into and later reactivate from a dormant persister state. Here, we provide ev...

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Detalles Bibliográficos
Autores principales: Connelly, Sean V., Manzella-Lapeira, Javier, Levine, Zoë C., Brzostowski, Joseph, Krymskaya, Ludmila, Rahman, Rifat S., Ellis, Angela C., Amin, Shuchi N., Sá, Juliana M., Wellems, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262848/
https://www.ncbi.nlm.nih.gov/pubmed/34044591
http://dx.doi.org/10.1128/mBio.00753-21

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