Identification of a High-Frequency Intrahost SARS-CoV-2 Spike Variant with Enhanced Cytopathic and Fusogenic Effects

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that is continuously evolving. Although its RNA-dependent RNA polymerase exhibits some exonuclease proofreading activity, viral sequence diversity can be produced by replication errors and host factors. A diversity of geneti...

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Detalles Bibliográficos
Autores principales: Rocheleau, Lynda, Laroche, Geneviève, Fu, Kathy, Stewart, Corina M., Mohamud, Abdulhamid O., Côté, Marceline, Giguère, Patrick M., Langlois, Marc-André, Pelchat, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262852/
https://www.ncbi.nlm.nih.gov/pubmed/34182784
http://dx.doi.org/10.1128/mBio.00788-21

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