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Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles

The immunogenicity of gp41-stabilized HIV-1 BG505 envelope (Env) trimers and nanoparticles (NPs) was recently assessed in mice and rabbits. Here, we combined Env-specific B-cell sorting and repertoire sequencing to identify neutralizing antibodies (NAbs) from immunized animals. A panel of mouse NAbs...

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Detalles Bibliográficos
Autores principales:	Kumar, Sonu, Lin, Xiaohe, Ngo, Timothy, Shapero, Benjamin, Sou, Cindy, Allen, Joel D., Copps, Jeffrey, Zhang, Lei, Ozorowski, Gabriel, He, Linling, Crispin, Max, Ward, Andrew B., Wilson, Ian A., Zhu, Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262854/ https://www.ncbi.nlm.nih.gov/pubmed/34156262 http://dx.doi.org/10.1128/mBio.00429-21

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