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Staphylococcal Protein A Induces Leukocyte Necrosis by Complexing with Human Immunoglobulins

One of the defining features of Staphylococcus aureus is its ability to evade and impair the human immune response through expression of staphylococcal protein A (SpA). Herein, we describe a previously unknown mechanism by which SpA can form toxic immune complexes when in the presence of human serum...

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Detalles Bibliográficos
Autores principales:	Fox, Proinnsias G., Schiavetti, Francesca, Rappuoli, Rino, McLoughlin, Rachel M., Bagnoli, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262926/ https://www.ncbi.nlm.nih.gov/pubmed/34060329 http://dx.doi.org/10.1128/mBio.00899-21

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