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Tryptophan Operon Diversity Reveals Evolutionary Trends among Geographically Disparate Chlamydia trachomatis Ocular and Urogenital Strains Affecting Tryptophan Repressor and Synthase Function

The obligate intracellular pathogen Chlamydia trachomatis (Ct) is the leading cause of bacterial sexually transmitted infections and blindness globally. To date, Ct urogenital strains are considered tryptophan prototrophs, utilizing indole for tryptophan synthesis within a closed-conformation tetram...

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Detalles Bibliográficos
Autores principales: Bommana, Sankhya, Somboonna, Naraporn, Richards, Gracie, Tarazkar, Maryam, Dean, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262981/
https://www.ncbi.nlm.nih.gov/pubmed/33975934
http://dx.doi.org/10.1128/mBio.00605-21