Multicomponent Gold-Linked Glycoconjugate Vaccine Elicits Antigen-Specific Humoral and Mixed T(H)1-T(H)17 Immunity, Correlated with Increased Protection against Burkholderia pseudomallei

Burkholderia pseudomallei is the causative agent of melioidosis, a fatal disease with a high mortality rate. The intrinsic resistance to commonly used antibiotics combined with the complex bacterial life cycle has hampered the development of preventive and therapeutic interventions and vaccines. Fur...

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Detalles Bibliográficos
Autores principales: Tapia, Daniel, Sanchez-Villamil, Javier I., Stevenson, Heather L., Torres, Alfredo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263005/
https://www.ncbi.nlm.nih.gov/pubmed/34182777
http://dx.doi.org/10.1128/mBio.01227-21

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