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Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii

Antibiotic-resistant strains of the Gram-negative pathogen Acinetobacter baumannii have emerged as a significant global health threat. One successful therapeutic option to treat bacterial infections has been to target the bacterial ribosome. However, in many cases, multidrug efflux pumps within the...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhemin, Morgan, Christopher E., Bonomo, Robert A., Yu, Edward W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263017/ https://www.ncbi.nlm.nih.gov/pubmed/34044590 http://dx.doi.org/10.1128/mBio.01031-21

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