Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

Most eukaryotic mRNAs accommodate alternative sites of poly(A) addition in the 3’ untranslated region in order to regulate mRNA function. Here, we present a systematic analysis of 3’ end formation factors, which revealed 3’UTR lengthening in response to a loss of the core machinery, whereas a loss o...

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Detalles Bibliográficos
Autores principales: Turner, Rachael Emily, Harrison, Paul F, Swaminathan, Angavai, Kraupner-Taylor, Calvin A, Goldie, Belinda J, See, Michael, Peterson, Amanda L, Schittenhelm, Ralf B, Powell, David R, Creek, Darren J, Dichtl, Bernhard, Beilharz, Traude H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263057/
https://www.ncbi.nlm.nih.gov/pubmed/34232857
http://dx.doi.org/10.7554/eLife.65331

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