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Evaluating distributional regression strategies for modelling self-reported sexual age-mixing

The age dynamics of sexual partnership formation determine patterns of sexually transmitted disease transmission and have long been a focus of researchers studying human immunodeficiency virus. Data on self-reported sexual partner age distributions are available from a variety of sources. We sought...

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Autores principales: Wolock, Timothy M, Flaxman, Seth, Risher, Kathryn A, Dadirai, Tawanda, Gregson, Simon, Eaton, Jeffrey W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263061/
https://www.ncbi.nlm.nih.gov/pubmed/34165078
http://dx.doi.org/10.7554/eLife.68318
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author Wolock, Timothy M
Flaxman, Seth
Risher, Kathryn A
Dadirai, Tawanda
Gregson, Simon
Eaton, Jeffrey W
author_facet Wolock, Timothy M
Flaxman, Seth
Risher, Kathryn A
Dadirai, Tawanda
Gregson, Simon
Eaton, Jeffrey W
author_sort Wolock, Timothy M
collection PubMed
description The age dynamics of sexual partnership formation determine patterns of sexually transmitted disease transmission and have long been a focus of researchers studying human immunodeficiency virus. Data on self-reported sexual partner age distributions are available from a variety of sources. We sought to explore statistical models that accurately predict the distribution of sexual partner ages over age and sex. We identified which probability distributions and outcome specifications best captured variation in partner age and quantified the benefits of modelling these data using distributional regression. We found that distributional regression with a sinh-arcsinh distribution replicated observed partner age distributions most accurately across three geographically diverse data sets. This framework can be extended with well-known hierarchical modelling tools and can help improve estimates of sexual age-mixing dynamics.
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spelling pubmed-82630612021-07-12 Evaluating distributional regression strategies for modelling self-reported sexual age-mixing Wolock, Timothy M Flaxman, Seth Risher, Kathryn A Dadirai, Tawanda Gregson, Simon Eaton, Jeffrey W eLife Epidemiology and Global Health The age dynamics of sexual partnership formation determine patterns of sexually transmitted disease transmission and have long been a focus of researchers studying human immunodeficiency virus. Data on self-reported sexual partner age distributions are available from a variety of sources. We sought to explore statistical models that accurately predict the distribution of sexual partner ages over age and sex. We identified which probability distributions and outcome specifications best captured variation in partner age and quantified the benefits of modelling these data using distributional regression. We found that distributional regression with a sinh-arcsinh distribution replicated observed partner age distributions most accurately across three geographically diverse data sets. This framework can be extended with well-known hierarchical modelling tools and can help improve estimates of sexual age-mixing dynamics. eLife Sciences Publications, Ltd 2021-06-24 /pmc/articles/PMC8263061/ /pubmed/34165078 http://dx.doi.org/10.7554/eLife.68318 Text en © 2021, Wolock et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Epidemiology and Global Health
Wolock, Timothy M
Flaxman, Seth
Risher, Kathryn A
Dadirai, Tawanda
Gregson, Simon
Eaton, Jeffrey W
Evaluating distributional regression strategies for modelling self-reported sexual age-mixing
title Evaluating distributional regression strategies for modelling self-reported sexual age-mixing
title_full Evaluating distributional regression strategies for modelling self-reported sexual age-mixing
title_fullStr Evaluating distributional regression strategies for modelling self-reported sexual age-mixing
title_full_unstemmed Evaluating distributional regression strategies for modelling self-reported sexual age-mixing
title_short Evaluating distributional regression strategies for modelling self-reported sexual age-mixing
title_sort evaluating distributional regression strategies for modelling self-reported sexual age-mixing
topic Epidemiology and Global Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263061/
https://www.ncbi.nlm.nih.gov/pubmed/34165078
http://dx.doi.org/10.7554/eLife.68318
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