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Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma

BACKGROUND: Schistosomiasis is highly prevalent in Africa. Praziquantel is effective against adult schistosomes but leaves prepatent stages unaffected—which is a limit to patient management and elimination. Given the large-scale use of praziquantel, development of drug resistance by Schistosoma is f...

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Detalles Bibliográficos
Autores principales:	Koehne, Erik, Zander, Nina, Rodi, Miriam, Held, Jana, Hoffmann, Wolfgang, Zoleko-Manego, Rella, Ramharter, Michael, Mombo-Ngoma, Ghyslain, Kremsner, Peter G., Kreidenweiss, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263063/ https://www.ncbi.nlm.nih.gov/pubmed/34166393 http://dx.doi.org/10.1371/journal.pntd.0009511

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