EPCT-03. SERIAL PLASMA AND CSF CELL-FREE TUMOR DNA (CF-TDNA) TRACKING IN DIFFUSE MIDLINE GLIOMA PATIENTS UNDERGOING TREATMENT WITH ONC201

Diffuse midline glioma (DMG) with the H3K27M mutation is a lethal childhood brain cancer, with patients rarely surviving 2 years from diagnosis. We conducted a multi-site Phase 1 trial of the imipridone ONC201 for children with H3K27M-mutant glioma (NCT03416530). Patients enrolled on Arm D of the tr...

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Detalles Bibliográficos
Autores principales: Cantor, Evan, Wierzbicki, Kyle, Tarapore, Rohinton S, Thomas, Chase, Cartaxo, Rodrigo, Yadav, Viveka Nand, Ravindran, Ramya, Bruzek, Amy K, Wadden, Jack, Babilla, Clarissa May, Kawakibi, Abed Rhaman, Ji, Sunjong, Ramos, Johanna, Paul, Alyssa, Wolfe, Ian, Leonard, Marcia, Robertson, Partricia, Franson, Andrea, Mody, Rajen, Garton, Hugh, Odia, Yazmin, Kline, Cassie, Vitanza, Nicholas A, Khatua, Soumen, Mueller, Sabine, Allen, Joshua E, Gardner, Sharon, Koschmann, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Translational/Early Phase Clinical Trials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263166/
http://dx.doi.org/10.1093/neuonc/noab090.189

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