Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome

We herein report a case of diffuse alveolar hemorrhage (DAH) associated with dilated cardiomyopathy (DCM) and sleep apnea syndrome (SAS) in a 47-year-old man. The patient exhibited recurring dyspnea and bloody sputum. Chest radiography showed bilateral diffuse infiltrative opacities without pleural...

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Autores principales: Suematsu, Ryohei, Miyata, Jun, Sano, Tomoya, Watanabe, Chie, Maki, Yohei, Kimizuka, Yoshifumi, Hayashi, Nobuyoshi, Fujikura, Yuji, Sugiura, Hiroaki, Shinmoto, Hiroshi, Taruoka, Akira, Nagatomo, Yuji, Adachi, Takeshi, Kawana, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263192/
https://www.ncbi.nlm.nih.gov/pubmed/33518557
http://dx.doi.org/10.2169/internalmedicine.5219-20
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author Suematsu, Ryohei
Miyata, Jun
Sano, Tomoya
Watanabe, Chie
Maki, Yohei
Kimizuka, Yoshifumi
Hayashi, Nobuyoshi
Fujikura, Yuji
Sugiura, Hiroaki
Shinmoto, Hiroshi
Taruoka, Akira
Nagatomo, Yuji
Adachi, Takeshi
Kawana, Akihiko
author_facet Suematsu, Ryohei
Miyata, Jun
Sano, Tomoya
Watanabe, Chie
Maki, Yohei
Kimizuka, Yoshifumi
Hayashi, Nobuyoshi
Fujikura, Yuji
Sugiura, Hiroaki
Shinmoto, Hiroshi
Taruoka, Akira
Nagatomo, Yuji
Adachi, Takeshi
Kawana, Akihiko
author_sort Suematsu, Ryohei
collection PubMed
description We herein report a case of diffuse alveolar hemorrhage (DAH) associated with dilated cardiomyopathy (DCM) and sleep apnea syndrome (SAS) in a 47-year-old man. The patient exhibited recurring dyspnea and bloody sputum. Chest radiography showed bilateral diffuse infiltrative opacities without pleural effusion. A bronchoscopic analysis of bronchoalveolar lavage fluid revealed hemosiderin-laden macrophages. Based on these findings, he was diagnosed with DAH. Laboratory and pathological findings ruled out the possibility of collagen diseases and vasculitis. Overnight polysomnography revealed concomitant severe obstructive SAS. Treatment with continuous positive-pressure ventilation and pharmacological therapy for DCM prevented recurrence of DAH.
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spelling pubmed-82631922021-07-12 Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome Suematsu, Ryohei Miyata, Jun Sano, Tomoya Watanabe, Chie Maki, Yohei Kimizuka, Yoshifumi Hayashi, Nobuyoshi Fujikura, Yuji Sugiura, Hiroaki Shinmoto, Hiroshi Taruoka, Akira Nagatomo, Yuji Adachi, Takeshi Kawana, Akihiko Intern Med Case Report We herein report a case of diffuse alveolar hemorrhage (DAH) associated with dilated cardiomyopathy (DCM) and sleep apnea syndrome (SAS) in a 47-year-old man. The patient exhibited recurring dyspnea and bloody sputum. Chest radiography showed bilateral diffuse infiltrative opacities without pleural effusion. A bronchoscopic analysis of bronchoalveolar lavage fluid revealed hemosiderin-laden macrophages. Based on these findings, he was diagnosed with DAH. Laboratory and pathological findings ruled out the possibility of collagen diseases and vasculitis. Overnight polysomnography revealed concomitant severe obstructive SAS. Treatment with continuous positive-pressure ventilation and pharmacological therapy for DCM prevented recurrence of DAH. The Japanese Society of Internal Medicine 2021-02-01 2021-06-15 /pmc/articles/PMC8263192/ /pubmed/33518557 http://dx.doi.org/10.2169/internalmedicine.5219-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Suematsu, Ryohei
Miyata, Jun
Sano, Tomoya
Watanabe, Chie
Maki, Yohei
Kimizuka, Yoshifumi
Hayashi, Nobuyoshi
Fujikura, Yuji
Sugiura, Hiroaki
Shinmoto, Hiroshi
Taruoka, Akira
Nagatomo, Yuji
Adachi, Takeshi
Kawana, Akihiko
Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome
title Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome
title_full Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome
title_fullStr Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome
title_full_unstemmed Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome
title_short Diffuse Alveolar Hemorrhage Associated with Dilated Cardiomyopathy and Sleep Apnea Syndrome
title_sort diffuse alveolar hemorrhage associated with dilated cardiomyopathy and sleep apnea syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263192/
https://www.ncbi.nlm.nih.gov/pubmed/33518557
http://dx.doi.org/10.2169/internalmedicine.5219-20
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