EPCT-04. RESULTS OF A PHASE 1 STUDY OF THE ONCOLYTIC ADENOVIRUS DNX-2401 WITH RADIOTHERAPY FOR NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

BACKGROUND: A Phase 1, single center study is ongoing to evaluate the conditionally replicative oncolytic adenovirus, DNX-2401 (tasadenoturev), followed by radiotherapy (RT) in pediatric patients with newly diagnosed diffuse intrinsic pontine glioma (DIPG). METHODS: Patients 1–18 years with newly di...

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Detalles Bibliográficos
Autores principales: Garcia-Moure, Marc, Pérez-Larraya, Jaime Gállego, Patiño, Ana, Gonzalez-Huarriz, Marisol, Jones, Chris, MacKay, Alan, Van der Lugt, Jasper, Hulleman, Esther, de Andrea, Carlos, Astigarraga, Itziar, García-Ariza, Miguel, Lopez-Ibor, Blanca, Villalba, Maria, Lang, Frederick F, Fueyo, Juan, Gomez-Manzano, Candelaria, Dobbs, Jessica, Diez-Valle, Ricardo, Alonso, Marta M, Tejada, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Translational/Early Phase Clinical Trials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263199/
http://dx.doi.org/10.1093/neuonc/noab090.190

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