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OMIC-05. PHOSPHOPROTEOMIC ANALYSIS IDENTIFIES SUBGROUP ENRICHED PATHWAYS AND KINASE SIGNATURES IN MEDULLOBLASTOMA
Medulloblastoma (MB) is classified into four molecular subgroups: wingless (WNT), sonic hedgehog (SHH), Group 3 (G3) and Group 4 (G4), each with different molecular profiles and patient outcomes. Subgroup heterogeneity and low mutational burdens have hindered the identification of actionable therape...
Autores principales: | Leskoske, Kristin, Garcia-Mansfield, Krystine, Krishnan, Aparna, Sharma, Ritin, Rusert, Jessica, Mesirov, Jill, Wechsler-Reya, Robert, Pirrotte, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263200/ http://dx.doi.org/10.1093/neuonc/noab090.152 |
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