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Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin

Chitinase-3-like-1 (CHI3L1) is known to induce inflammation in the progression of allergic diseases. Previous our studies revealed that 2-({3-[2-(1-cyclohexen-1-yl)ethyl]-6,7-dimethoxy-4-oxo-3,4-dihydro-2-quinazolinyl}sulfanyl)-N-(4-ethylphenyl)butanamide (K284-6111; K284), the CHI3L1 inhibiting com...

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Detalles Bibliográficos
Autores principales:	Jeon, Seong Hee, Lee, Yong Sun, Yeo, In Jun, Lee, Hee Pom, Yoon, Jaesuk, Son, Dong Ju, Han, Sang-Bae, Hong, Jin Tae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Association of Immunologists 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263211/ https://www.ncbi.nlm.nih.gov/pubmed/34277112 http://dx.doi.org/10.4110/in.2021.21.e22

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