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Heart Dissemination: A Clinical Case of Melanoma

Introduction. Primitive malignant heart tumours are rare, specific cases. The presence of cardiac metastases, often in the pericardium, besides indicating disseminated oncological disease, represents a diagnostic challenge since they tend to be asymptomatic. Malignant cutaneous melanoma (MCM) is the...

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Autores principales: André, Diogo, André, Teresa, Gouveia, Fabiana, Nascimento, Rafael, Chaves, António, Braza˜o, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263222/
https://www.ncbi.nlm.nih.gov/pubmed/34306093
http://dx.doi.org/10.1155/2021/8562402
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author André, Diogo
André, Teresa
Gouveia, Fabiana
Nascimento, Rafael
Chaves, António
Braza˜o, Maria
author_facet André, Diogo
André, Teresa
Gouveia, Fabiana
Nascimento, Rafael
Chaves, António
Braza˜o, Maria
author_sort André, Diogo
collection PubMed
description Introduction. Primitive malignant heart tumours are rare, specific cases. The presence of cardiac metastases, often in the pericardium, besides indicating disseminated oncological disease, represents a diagnostic challenge since they tend to be asymptomatic. Malignant cutaneous melanoma (MCM) is the neoplasm that most often affects the heart. Patients and Methods. The authors describe a case report of a 59-year-old female patient with a history of non-insulin-treated diabetes mellitus, arterial hypertension, dyslipidemia, and remitting cutaneous malignant melanoma who underwent skin excision, lymphadenectomy, and adjuvant chemotherapy in 1996. In April 2014, she resorted to emergency service due to epigastric pain and progressive tiredness. Due to the persistence of the complaints, abdominal ultrasound was performed, which showed a large pericardial effusion, corroborated later by teleradiography and echocardiography. The patient underwent pericardiocentesis, which isolated neoplastic cells. A computed tomography study of the chest, abdomen, and pelvis revealed bilateral and pericardial pleural effusion, as well as alterations suggestive of pericardial and pulmonary metastasis. Later, fine-needle aspiration puncture of the left posterior cervical nodule confirmed histologically malignant melanoma metastasis. Discussion. Given the natural history of melanoma that when metastasized has an overall survival of 15–20% for 5 years, its metastatic spread may occur several years after its surgical excision. Thus, patients with a history of melanoma and heart failure who develop new cardiac symptoms of unknown aetiology should undergo imaging studies such as echocardiography, computed tomography, and magnetic resonance imaging.
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spelling pubmed-82632222021-07-22 Heart Dissemination: A Clinical Case of Melanoma André, Diogo André, Teresa Gouveia, Fabiana Nascimento, Rafael Chaves, António Braza˜o, Maria Case Rep Med Case Report Introduction. Primitive malignant heart tumours are rare, specific cases. The presence of cardiac metastases, often in the pericardium, besides indicating disseminated oncological disease, represents a diagnostic challenge since they tend to be asymptomatic. Malignant cutaneous melanoma (MCM) is the neoplasm that most often affects the heart. Patients and Methods. The authors describe a case report of a 59-year-old female patient with a history of non-insulin-treated diabetes mellitus, arterial hypertension, dyslipidemia, and remitting cutaneous malignant melanoma who underwent skin excision, lymphadenectomy, and adjuvant chemotherapy in 1996. In April 2014, she resorted to emergency service due to epigastric pain and progressive tiredness. Due to the persistence of the complaints, abdominal ultrasound was performed, which showed a large pericardial effusion, corroborated later by teleradiography and echocardiography. The patient underwent pericardiocentesis, which isolated neoplastic cells. A computed tomography study of the chest, abdomen, and pelvis revealed bilateral and pericardial pleural effusion, as well as alterations suggestive of pericardial and pulmonary metastasis. Later, fine-needle aspiration puncture of the left posterior cervical nodule confirmed histologically malignant melanoma metastasis. Discussion. Given the natural history of melanoma that when metastasized has an overall survival of 15–20% for 5 years, its metastatic spread may occur several years after its surgical excision. Thus, patients with a history of melanoma and heart failure who develop new cardiac symptoms of unknown aetiology should undergo imaging studies such as echocardiography, computed tomography, and magnetic resonance imaging. Hindawi 2021-06-30 /pmc/articles/PMC8263222/ /pubmed/34306093 http://dx.doi.org/10.1155/2021/8562402 Text en Copyright © 2021 Diogo André et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
André, Diogo
André, Teresa
Gouveia, Fabiana
Nascimento, Rafael
Chaves, António
Braza˜o, Maria
Heart Dissemination: A Clinical Case of Melanoma
title Heart Dissemination: A Clinical Case of Melanoma
title_full Heart Dissemination: A Clinical Case of Melanoma
title_fullStr Heart Dissemination: A Clinical Case of Melanoma
title_full_unstemmed Heart Dissemination: A Clinical Case of Melanoma
title_short Heart Dissemination: A Clinical Case of Melanoma
title_sort heart dissemination: a clinical case of melanoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263222/
https://www.ncbi.nlm.nih.gov/pubmed/34306093
http://dx.doi.org/10.1155/2021/8562402
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