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Transcriptomic analysis links hepatocellular carcinoma (HCC) in HZE ion irradiated mice to a human HCC subtype with favorable outcomes

High-charge, high-energy ion particle (HZE) radiations are extraterrestrial in origin and characterized by high linear energy transfer (high-LET), which causes more severe cell damage than low-LET radiations like γ-rays or photons. High-LET radiation poses potential cancer risks for astronauts on de...

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Detalles Bibliográficos
Autores principales: Ding, Liang-Hao, Yu, Yongjia, Edmondson, Elijah F., Weil, Michael. M., Pop, Laurentiu M., McCarthy, Maureen, Ullrich, Robert L., Story, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263559/
https://www.ncbi.nlm.nih.gov/pubmed/34234215
http://dx.doi.org/10.1038/s41598-021-93467-3