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Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2
Cleavage and dissociation of a large N-terminal fragment and the consequent unmasking of a short sequence (Stachel) remaining on the N-terminus have been proposed as mechanisms of activation of some members of the adhesion G protein-coupled receptor (aGPCR) family. However, the identity of residues...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263569/ https://www.ncbi.nlm.nih.gov/pubmed/34234254 http://dx.doi.org/10.1038/s41598-021-93577-y |