Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis

Cell-free DNA (cfDNA) is attractive for many applications, including detecting cancer, identifying the tissue of origin, and monitoring. A fundamental task underlying these applications is SNV calling from cfDNA, which is hindered by the very low tumor content. Thus sensitive and accurate detection...

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Detalles Bibliográficos
Autores principales: Li, Shuo, Noor, Zorawar S., Zeng, Weihua, Stackpole, Mary L., Ni, Xiaohui, Zhou, Yonggang, Yuan, Zuyang, Wong, Wing Hung, Agopian, Vatche G., Dubinett, Steven M., Alber, Frank, Li, Wenyuan, Garon, Edward B., Zhou, Xianghong Jasmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263778/
https://www.ncbi.nlm.nih.gov/pubmed/34234141
http://dx.doi.org/10.1038/s41467-021-24457-2

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