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Improved genetic prediction of complex traits from individual-level data or summary statistics
Most existing tools for constructing genetic prediction models begin with the assumption that all genetic variants contribute equally towards the phenotype. However, this represents a suboptimal model for how heritability is distributed across the genome. Therefore, we develop prediction tools that...
Autores principales: | Zhang, Qianqian, Privé, Florian, Vilhjálmsson, Bjarni, Speed, Doug |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263809/ https://www.ncbi.nlm.nih.gov/pubmed/34234142 http://dx.doi.org/10.1038/s41467-021-24485-y |
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