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Irradiation-Modulated Murine Brain Microenvironment Enhances GL261-Tumor Growth and Inhibits Anti-PD-L1 Immunotherapy
PURPOSE: Clinical evidence suggests radiation induces changes in the brain microenvironment that affect subsequent response to treatment. This study investigates the effect of previous radiation, delivered six weeks prior to orthotopic tumor implantation, on subsequent tumor growth and therapeutic r...
Autores principales: | Garbow, Joel R., Johanns, Tanner M., Ge, Xia, Engelbach, John A., Yuan, Liya, Dahiya, Sonika, Tsien, Christina I., Gao, Feng, Rich, Keith M., Ackerman, Joseph J. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263916/ https://www.ncbi.nlm.nih.gov/pubmed/34249742 http://dx.doi.org/10.3389/fonc.2021.693146 |
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