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Mutant p53 and Twist1 Co-Expression Predicts Poor Prognosis and Is an Independent Prognostic Factor in Breast Cancer

PURPOSE: The basic helix-loop-helix transcription factor (bHLH) transcription factor Twist1 plays a key role in embryonic development and tumorigenesis. p53 is a frequently mutated tumor suppressor in cancer. Both proteins play a key and significant role in breast cancer tumorigenesis. However, the...

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Detalles Bibliográficos
Autores principales: Zhang, Yong-Qu, Zhang, Fan, Zeng, Yun-Zhu, Chen, Min, Huang, Wen-He, Wu, Jun-Dong, Chen, Wei-Ling, Gao, Wen-Liang, Bai, Jing-Wen, Yang, Rui-Qin, Zeng, Huan-Cheng, Wei, Xiao-Long, Zhang, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263931/
https://www.ncbi.nlm.nih.gov/pubmed/34249678
http://dx.doi.org/10.3389/fonc.2021.628814