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Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis

Aims: Is there evidence for increased psychological distress and alterations in personality functioning in patients with Crohn’s disease (CD) and ulcerative colitis (UC) compared to healthy controls (HCs)? Background: In patients with CD and UC, perceived stress is closely associated with changes in...

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Autores principales: Engel, Felicitas, Berens, Sabrina, Gauss, Annika, Schaefert, Rainer, Eich, Wolfgang, Tesarz, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264053/
https://www.ncbi.nlm.nih.gov/pubmed/34248767
http://dx.doi.org/10.3389/fpsyg.2021.671493
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author Engel, Felicitas
Berens, Sabrina
Gauss, Annika
Schaefert, Rainer
Eich, Wolfgang
Tesarz, Jonas
author_facet Engel, Felicitas
Berens, Sabrina
Gauss, Annika
Schaefert, Rainer
Eich, Wolfgang
Tesarz, Jonas
author_sort Engel, Felicitas
collection PubMed
description Aims: Is there evidence for increased psychological distress and alterations in personality functioning in patients with Crohn’s disease (CD) and ulcerative colitis (UC) compared to healthy controls (HCs)? Background: In patients with CD and UC, perceived stress is closely associated with changes in disease activity. The stress response is influenced by psychological burden and personality functioning, but only little is known about these factors in inflammatory bowel diseases (IBD). Study: A total of 62 patients with an endoscopic ensured CD/UC without remission (n = 31 per group) and 31 HC were included. Patients with an active CD/UC and HC were individually matched (n = 93, 31 per group) for age, sex, education, and disease activity. Depression and anxiety were assessed to evaluate the effect of psychological burden (Patient Health Questionnaire-9/PHQ-9, Generalized Anxiety Disorder-7/GAD-7). Personality functioning was measured by validated questionnaires for psychodynamic structural characteristics, mentalization, and attachment (Operationalized Psychodynamic Diagnosis-Structure Questionnaire/OPD-SQ, Mentalization Questionnaire/MZQ, and Experiences in Close Relationships scale/ECR-RD 12). Results: Levels of depression and anxiety were higher in CD/UC patients than in HC with large effect sizes. Comparing personality functioning in CD/UC with HC, psychodynamic structural characteristics differed between CD/UC and HC with medium effect sizes, with structural differences occurring primarily in the domain of self-perception and regulation. Only minor differences were found regarding mentalization and attachment. CD and UC differed only with small effect sizes. Conclusion: Our data show that compared to HC, patients with CD/UC are characterized by a higher level of psychological burden and structural alterations in the domain of self.
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spelling pubmed-82640532021-07-09 Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis Engel, Felicitas Berens, Sabrina Gauss, Annika Schaefert, Rainer Eich, Wolfgang Tesarz, Jonas Front Psychol Psychology Aims: Is there evidence for increased psychological distress and alterations in personality functioning in patients with Crohn’s disease (CD) and ulcerative colitis (UC) compared to healthy controls (HCs)? Background: In patients with CD and UC, perceived stress is closely associated with changes in disease activity. The stress response is influenced by psychological burden and personality functioning, but only little is known about these factors in inflammatory bowel diseases (IBD). Study: A total of 62 patients with an endoscopic ensured CD/UC without remission (n = 31 per group) and 31 HC were included. Patients with an active CD/UC and HC were individually matched (n = 93, 31 per group) for age, sex, education, and disease activity. Depression and anxiety were assessed to evaluate the effect of psychological burden (Patient Health Questionnaire-9/PHQ-9, Generalized Anxiety Disorder-7/GAD-7). Personality functioning was measured by validated questionnaires for psychodynamic structural characteristics, mentalization, and attachment (Operationalized Psychodynamic Diagnosis-Structure Questionnaire/OPD-SQ, Mentalization Questionnaire/MZQ, and Experiences in Close Relationships scale/ECR-RD 12). Results: Levels of depression and anxiety were higher in CD/UC patients than in HC with large effect sizes. Comparing personality functioning in CD/UC with HC, psychodynamic structural characteristics differed between CD/UC and HC with medium effect sizes, with structural differences occurring primarily in the domain of self-perception and regulation. Only minor differences were found regarding mentalization and attachment. CD and UC differed only with small effect sizes. Conclusion: Our data show that compared to HC, patients with CD/UC are characterized by a higher level of psychological burden and structural alterations in the domain of self. Frontiers Media S.A. 2021-06-24 /pmc/articles/PMC8264053/ /pubmed/34248767 http://dx.doi.org/10.3389/fpsyg.2021.671493 Text en Copyright © 2021 Engel, Berens, Gauss, Schaefert, Eich and Tesarz. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Engel, Felicitas
Berens, Sabrina
Gauss, Annika
Schaefert, Rainer
Eich, Wolfgang
Tesarz, Jonas
Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis
title Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis
title_full Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis
title_fullStr Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis
title_full_unstemmed Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis
title_short Higher Levels of Psychological Burden and Alterations in Personality Functioning in Crohn’s Disease and Ulcerative Colitis
title_sort higher levels of psychological burden and alterations in personality functioning in crohn’s disease and ulcerative colitis
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264053/
https://www.ncbi.nlm.nih.gov/pubmed/34248767
http://dx.doi.org/10.3389/fpsyg.2021.671493
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