Immune checkpoint blockade impairs immunosuppressive mechanisms of regulatory T cells in B-cell lymphoma

In malignant disease, CD4(+)Foxp3(+) regulatory T cells (Tregs) hamper antitumor immune responses and may provide a target for immunotherapy. Although immune checkpoint blockade (ICB) has become an established therapy for several cancer entities including lymphoma, its mechanisms have not been entir...

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Detalles Bibliográficos
Autores principales: Bauer, Vera, Ahmetlić, Fatima, Hömberg, Nadine, Geishauser, Albert, Röcken, Martin, Mocikat, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264214/
https://www.ncbi.nlm.nih.gov/pubmed/34229208
http://dx.doi.org/10.1016/j.tranon.2021.101170

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