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Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway

Ferroptosis is primarily triggered by a failure of the glutathione (GSH)-glutathione peroxidase 4 (GPX4) reductive system and associated overwhelming lipid peroxidation, in which enzymes regulating polyunsaturated fatty acid (PUFA) metabolism, and in particular acyl-CoA synthetase long chain family...

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Detalles Bibliográficos
Autores principales:	Shui, Sufang, Zhao, Zenglu, Wang, Hao, Conrad, Marcus, Liu, Guoquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264218/ https://www.ncbi.nlm.nih.gov/pubmed/34229160 http://dx.doi.org/10.1016/j.redox.2021.102056

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