Cargando…

New mechanistic insights into hepatoprotective activity of milk thistle and chicory quantified extract: The role of hepatic Farnesoid-X activated receptors

OBJECTIVE: Farnesoid-X-activated receptors (FXR) are key modulators of liver regeneration. Milk thistle and Chicory are known as potent protective remedies in several liver disorders. The objective of this work was to examine the role of FXR in the hepato-healing properties of milk thistle (MTE) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khalili, Azadeh, Fallah, Parviz, Hashemi, Seyed Ali, Ahmadian-Attari, Mohammad Mahdi, Jamshidi, Vahid, Mazloom, Roham, Beikzadeh, Leila, Bayat, Gholamreza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2021
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264225/ https://www.ncbi.nlm.nih.gov/pubmed/34290968 http://dx.doi.org/10.22038/AJP.2020.17281

Ejemplares similares

Saffron offers hepatoprotection via up-regulation of hepatic farnesoid-X-activated receptors in a rat model of acetaminophen-induced hepatotoxicity
por: Jamshidi, Vahid, et al.
Publicado: (2021)

Silymarin Administration Attenuates Cirrhotic-induced Cardiac Abnormality in the Rats: A Possible Role of β(1)-adrenergic Receptors and L-type Voltage-Dependent Calcium Channels
por: Bayat, Gholamreza, et al.
Publicado: (2022)

Hepatoprotective effect of feeding celery leaves mixed with chicory leaves and barley grains to hypercholesterolemic rats
por: Abd El-Mageed, Nehal M.
Publicado: (2011)

Hepatoprotective effects of parsley, basil, and chicory aqueous extracts against dexamethasone-induced in experimental rats
por: Soliman, Hanan A., et al.
Publicado: (2016)

Cisplatin Nephrotoxicity and Protection by Milk Thistle Extract in Rats
por: Karimi, Gholamreza, et al.
Publicado: (2005)

The effects of milk thistle on hepatic fibrosis due to methotrexate in rat
por: Ghaffari, Ali Reza, et al.
Publicado: (2011)

Hepatoprotective Effects of Nonpolar Extracts from Inflorescences of Thistles Cirsium vulgare and Cirsium ehrenbergii on Acute Liver Damage in Rat
por: Fernández-Martínez, Eduardo, et al.
Publicado: (2017)

Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery
por: Mirhashemi, Seyed Hadi, et al.
Publicado: (2022)

Theoretical Assessment of Therapeutic Effects of Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors on COVID-19
por: Khalili, Azadeh, et al.
Publicado: (2021)

Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer
por: Fallah, Maryam, et al.
Publicado: (2021)

Phytochemical Profile, Antioxidant, Cardioprotective and Nephroprotective Activity of Romanian Chicory Extract
por: Epure, Alexandra, et al.
Publicado: (2020)

Feasibility of Therapeutic Effects of the Cholinergic Anti-Inflammatory Pathway on COVID-19 Symptoms
por: Mazloom, Roham
Publicado: (2020)

Liposomal and Non-Liposomal Formulations of Vitamin C: Comparison of the Antihypertensive and Vascular Modifying Activity in Renovascular Hypertensive Rats
por: Khalili, Azadeh, et al.
Publicado: (2020)

Warming Increases the Spread of an Invasive Thistle
por: Zhang, Rui, et al.
Publicado: (2011)

Cannabidiol interacts with the FXR/Nrf2 pathway and changes the CB1/CB2 receptors ratio in gentamicin-induced kidney injury in rats
por: Hokmabadi, Vahideh, et al.
Publicado: (2023)

LC-ESI/QTOF-MS Profiling of Chicory and Lucerne Polyphenols and Their Antioxidant Activities
por: Iqbal, Yasir, et al.
Publicado: (2021)

Bacterial metabolites directly modulate farnesoid X receptor activity
por: Zhang, Xianqin, et al.
Publicado: (2015)

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model
por: Wang, Xiaoxin X., et al.
Publicado: (2010)

Antioxidant and Anti-Hepatitis C Viral Activities of Commercial Milk Thistle Food Supplements
por: Anthony, Kevin, et al.
Publicado: (2013)

A Water-Soluble Microencapsulated Milk Thistle Extract as Active Ingredient for Dermal Formulations
por: Esposito, Tiziana, et al.
Publicado: (2019)

Chicory Extracts and Sesquiterpene Lactones Show Potent Activity against Bacterial and Fungal Pathogens
por: Häkkinen, Suvi T., et al.
Publicado: (2021)

Adaptive plasticity and niche expansion in an invasive thistle
por: Turner, Kathryn G, et al.
Publicado: (2015)

Plant community associations of two invasive thistles
por: Rauschert, Emily S.J., et al.
Publicado: (2015)

Chicory: Understanding the Effects and Effectors of This Functional Food
por: Pouille, Céline L., et al.
Publicado: (2022)

Antiosteoclastic Activity of Milk Thistle Extract after Ovariectomy to Suppress Estrogen Deficiency-Induced Osteoporosis
por: Kim, Jung-Lye, et al.
Publicado: (2013)

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review
por: Peña-Espinoza, Miguel, et al.
Publicado: (2018)

Activated farnesoid X receptor attenuates apoptosis and liver injury in autoimmune hepatitis
por: LIAN, FAN, et al.
Publicado: (2015)

Farnesoid X Receptor Activation Attenuates Intestinal Ischemia Reperfusion Injury in Rats
por: Ceulemans, Laurens J., et al.
Publicado: (2017)

Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage
por: Gai, Zhibo, et al.
Publicado: (2017)

Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis
por: Tschuck, Juliane, et al.
Publicado: (2023)

Effects of platelet‐rich plasma on the memory impairment, apoptosis, and hippocampal synaptic plasticity in a rat model of hepatic encephalopathy
por: Bayat, Mahnaz, et al.
Publicado: (2021)

Comparative impacts of aboveground and belowground enemies on an invasive thistle
por: Nunes, Krystal A., et al.
Publicado: (2017)

In vitro culture, transformation and genetic fidelity of Milk Thistle
por: Rady, M.R., et al.
Publicado: (2018)

Hepatoprotective Activity of Kadhaka Kadhiradi Kashayam
por: Sundari, S. Karpagm Kumara, et al.
Publicado: (2000)

Biogenic selenium and its hepatoprotective activity
por: Li, Baozhen, et al.
Publicado: (2017)

The Farnesoid X Receptor: Good for BAD
por: Keely, Stephen J., et al.
Publicado: (2016)

Protection against neonatal enteric colibacillosis employing E. Coli-derived outer membrane vesicles in formulation and without vitamin D3
por: Beikzadeh, Babak, et al.
Publicado: (2018)

Identification of Isosilybin A from Milk Thistle Seeds as an Agonist of Peroxisome Proliferator-Activated Receptor Gamma
por: Pferschy-Wenzig, Eva-Maria, et al.
Publicado: (2014)

Hypoglycemic and hypolipidemic activity of combined milk thistle and fenugreek seeds in alloxan-induced diabetic albino rats
por: Saadh, Mohamed Jamal
Publicado: (2020)

Antimicrobial and anti-adherence activity of various combinations of coffee-chicory solutions on Streptococcus mutans: An in-vitro study
por: Sharma, Rama, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9h4phm4ns9qbctveefjtn41cef