Cargando…

Early ART initiation during infancy preserves natural killer cells in young European adolescents living with HIV (CARMA cohort)

INTRODUCTION: HIV infection causes pathological changes in the natural killer (NK) cell compartment that can be only partially restored by antiretroviral therapy (ART). We investigated NK cells phenotype and function in children with perinatally acquired HIV (PHIV) and long‐term viral control (five...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doria, Margherita, Zicari, Sonia, Cotugno, Nicola, Domínguez‐Rodríguez, Sara, Ruggiero, Alessandra, Pascucci, Giuseppe R, Tagarro, Alfredo, Rojo Conejo, Pablo, Nastouli, Eleni, Gärtner, Kathleen, Cameron, Mark, Richardson, Brian, Foster, Caroline, Williams, Sion L, Rinaldi, Stefano, De Rossi, Anita, Giaquinto, Carlo, Rossi, Paolo, Pahwa, Savita, Palma, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264399/ https://www.ncbi.nlm.nih.gov/pubmed/34235857 http://dx.doi.org/10.1002/jia2.25717

Ejemplares similares

Clinical, Virological and Immunological Subphenotypes in a Cohort of Early Treated HIV-Infected Children
por: Domínguez-Rodríguez, Sara, et al.
Publicado: (2022)

The CARMA Study: Early Infant Antiretroviral Therapy—Timing Impacts on Total HIV-1 DNA Quantitation 12 Years Later
por: Foster, Caroline, et al.
Publicado: (2020)

Size of HIV‐1 reservoir is associated with telomere shortening and immunosenescence in early‐treated European children with perinatally acquired HIV‐1
por: Dalzini, Annalisa, et al.
Publicado: (2021)

Determinants of B-Cell Compartment Hyperactivation in European Adolescents Living With Perinatally Acquired HIV-1 After Over 10 Years of Suppressive Therapy
por: Ruggiero, Alessandra, et al.
Publicado: (2022)

T cell immune discriminants of HIV reservoir size in a pediatric cohort of perinatally infected individuals
por: Rinaldi, Stefano, et al.
Publicado: (2021)

DNAM-1 Activating Receptor and Its Ligands: How Do Viruses Affect the NK Cell-Mediated Immune Surveillance during the Various Phases of Infection?
por: Cifaldi, Loredana, et al.
Publicado: (2019)

Artificial Intelligence Applied to in vitro Gene Expression Testing (IVIGET) to Predict Trivalent Inactivated Influenza Vaccine Immunogenicity in HIV Infected Children
por: Cotugno, Nicola, et al.
Publicado: (2020)

Paediatric HIV infection in the ‘omics era: defining transcriptional signatures of viral control and vaccine responses
por: Cotugno, Nicola, et al.
Publicado: (2015)

Perturbation of B Cell Gene Expression Persists in HIV-Infected Children Despite Effective Antiretroviral Therapy and Predicts H1N1 Response
por: Cotugno, Nicola, et al.
Publicado: (2017)

B-cell immunity and vaccine induced antibody protection reveal the inefficacy of current vaccination schedule in infants with perinatal HIV-infection in Mozambique, Africa
por: Cotugno, Nicola, et al.
Publicado: (2023)

Report from the First EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children's Actual Life with Novel Immunotherapeutic Strategies) General Assembly meeting, 9–11 November 2017, Rome, Italy
por: Zangari, P, et al.
Publicado: (2018)

Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies
por: Cotugno, Nicola, et al.
Publicado: (2021)

Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy
por: de Armas, Lesley R., et al.
Publicado: (2019)

Suboptimal Immune Reconstitution in Vertically HIV Infected Children: A View on How HIV Replication and Timing of HAART Initiation Can Impact on T and B-cell Compartment
por: Cotugno, Nicola, et al.
Publicado: (2012)

OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines
por: Cotugno, Nicola, et al.
Publicado: (2019)

The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children
por: Palma, P, et al.
Publicado: (2015)

How CD4(+) T Cells Transcriptional Profile Is Affected by Culture Conditions: Towards the Design of Optimal In Vitro HIV Reactivation Assays
por: Pascucci, Giuseppe Rubens, et al.
Publicado: (2023)

Taxonomic classification of metagenomic shotgun sequences with CARMA3
por: Gerlach, Wolfgang, et al.
Publicado: (2011)

Structural Insights into the Assembly of CARMA1 and BCL10
por: Li, Siwei, et al.
Publicado: (2012)

Immune Activation, Inflammation, and Non-AIDS Co-Morbidities in HIV-Infected Patients under Long-Term ART
por: Zicari, Sonia, et al.
Publicado: (2019)

The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
por: Consiglio, Camila Rosat, et al.
Publicado: (2020)

Editorial: CARMA Proteins: Playing a Hand of Four CARDs
por: Bornancin, Frédéric, et al.
Publicado: (2019)

Research on English Achievement Analysis Based on Improved CARMA Algorithm
por: Hu, Lin
Publicado: (2022)

IκB kinase β–induced phosphorylation of CARMA1 contributes to CARMA1–Bcl10–MALT1 complex formation in B cells
por: Shinohara, Hisaaki, et al.
Publicado: (2007)

Viral Response among Early Treated HIV Perinatally Infected Infants: Description of a Cohort in Southern Mozambique
por: Lain, Maria Grazia, et al.
Publicado: (2022)

The Dishevelled, EGL-10 and Pleckstrin (DEP) Domain-Containing Protein DEPDC7 Binds to CARMA2 and CARMA3 Proteins, and Regulates NF-κB Activation
por: D′ Andrea, Egildo Luca, et al.
Publicado: (2014)

Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence
por: Fernández-Luis, Sheila, et al.
Publicado: (2022)

Paradoxical aging in HIV: immune senescence of B Cells is most prominent in young age
por: Rinaldi, Stefano, et al.
Publicado: (2017)

CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
por: Greer, Kevin A, et al.
Publicado: (2006)

Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery
por: Barnes, Michael J, et al.
Publicado: (2009)

CARMA3: Scaffold Protein Involved in NF-κB Signaling
por: Zhang, Shilei, et al.
Publicado: (2019)

V-CARMA: A tool for the detection and modification of antigen-specific T cells
por: Guo, Xi-zhi J., et al.
Publicado: (2022)

CARMA3: A potential therapeutic target in non-cancer diseases
por: Gui, Zhen, et al.
Publicado: (2022)

CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship
por: Scudiero, Ivan, et al.
Publicado: (2017)

Perinatally Human Immunodeficiency Virus–Infected Adolescents and Young Adults Demonstrate Distinct BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccine Immunogenicity( )
por: Morrocchi, Elena, et al.
Publicado: (2022)

Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies
por: Juilland, Mélanie, et al.
Publicado: (2016)

CARD14/CARMA2 Signaling and its Role in Inflammatory Skin Disorders
por: Zotti, Tiziana, et al.
Publicado: (2018)

HIV-1 reservoir evolution in infants infected with clade C from Mozambique
por: Koofhethile, Catherine K., et al.
Publicado: (2023)

WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic reads
por: Gerlach, Wolfgang, et al.
Publicado: (2009)

Overexpression of CARMA3 in Non-Small-Cell Lung Cancer Is Linked for Tumor Progression
por: Li, Zixuan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_5p9csokuk2jevq5q7fakmraqb9